What is hemp oil?

Hemp, is a variety of the Cannabis sativa plant species that is grown specifically for the industrial uses of its derived products. Unlike marijuana, another variety of Cannabis plant, hemp does not have psychoactive effects. You will not get “high” from hemp, which is part of the reason why it is legal in most parts of the world, and why it is an excellent choice for people who wish to avail of the many benefits of hemp without the psychoactive effects of marijuana.

How does it work?

Hemp primarily interacts with the 

body’s natural endocannabinoid system.

Almost every organ in your body contains cannabinoid receptors that react to naturally occurring cannabinoids produced in your body, known as endocannabinoids. Hemp contains plant-based cannabinoids, called phytocannabinoids.

The endocannabinoid system has four primary purposes:

  1. Neuroprotection
  2. Stress relief
  3. Immune response
  4. Regulating the body’s general state of balance

Unlike marijuana, hemp does not interact directly with the two cannabinoid receptors CB1 and CB2. This is why hemp does not cause any psychoactive effects. Instead, hemp activates other receptors, like the vanilloid, adenosine and serotonin receptors.

What receptors can hemp affect?

By activating the TRPV-1 receptor, hemp plays a role in the mediation of body temperature, pain perception and inflammation

Hemp inhibits the FAAH enzyme, a compound that activates the CB1 receptor. By doing so, hemp minimizes the activation of CB1 by THC, reducing its psychoactive effects.

The activation of adenosine receptors by hemp gives anti-anxiety and anti-inflammatory effects. Adenosine receptors are also involved in the release of dopamine and glutamate, two neurotransmitters that play major roles inside the body. Dopamine is involved in cognition, motor control, motivation and reward mechanisms, while glutamate is one of the major mediators of excitatory signals, being involved in memory, learning and cognition.

High concentrations of hemp have been shown to activate the 5-HT1A serotonin receptor, exerting anti-depressant effects. The same receptor is involved in a series of processes from pain perception, appetite, nausea and anxiety to sleep and addiction mechanisms.

Finally, hemp blocks CPR55 signaling, decreasing bone re-absorption and cancer cell proliferation. GPR55 is widely present inside the brain, being linked with the modulation of bone density and blood pressure, as well as with cancer cell proliferation.

What conditions can hemp oil help with?

Hemp has been proven to be extremely beneficial in treating hundreds of illnesses. We have compiled a short list below, but there are countless others. Hemp truly is a miraculous plant!

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Wikipedia (2019). Hemp. Retrieved from https://en.wikipedia.org/wiki/Hemp